OLR1 and atherosclerosis: LOX-1 is expressed on vascular endothelial cells, smooth muscle cells, platelets, fibroblasts and macrophages and its expression can be upregulated by a variety of proinflammatory, oxidative and mechanical stimuli and during several pathological conditions in vivo, such as diabetes, hyperlipidemia, atherosclerosis and hypertension (reviewed in Chen & Du, 2007; Dunn et al., 2008).