This result seems to be partially consistent with a previous report [16], in which circulating IGFBP7 levels in non-diabetic men correlated negatively with serum adiponectin levels, and positively with serum C-reactive protein (CRP) and soluble tumor necrosis factor receptor 2 (sTNFR2) levels, indicating that IGFBP7 is associated with insulin resistance. This evidence concerns the gene CRP and Insulin resistance.