In contrast, KIT mutations are rarely found in the major subtype of cutaneous melanoma originating from skin without chronic sun damage (Curtin et al, 2006) and unselected cutaneous melanomas (2 out of 100 in Willmore-Payne et al (2005); 1 out of 39 in Went et al (2004)). This evidence concerns the gene KIT and cutaneous melanoma.