PPARG and brain neoplasm: Interestingly, recent studies have shown that PPARγ is expressed in normal and malignant human brain and that treatment with PPARγ agonists induces growth arrest and apoptosis in brain tumour cells in vitro and in animal models in vivo (Strakova et al, 2004, 2005; Cellai et al, 2006; Grommes et al, 2006), but their effects on BTSCs are unknown.