Various researchers have found an abnormally high expression of PTTG1 in a wide range of human primary tumors such as those found in the ovary, testis, kidney, colon, thyroid, pituitary, liver, adrenal, and breast as well as in a range of tumor cell lines such as melanoma, leukemia, and lymphoma [9,12,15,19,25,53,55,63,79,96-98]. This evidence concerns the gene PTTG1 and neoplasm.