Cytokines, such as TNF-α, IL-1, and IL-6, can also induce expression of ST6Gal-I [25,26], and interestingly, IL-1 and IL-6 have been shown to increase ovarian carcinoma cell motility and metastasis, as well as being able to up-regulate TNF-α production [27,28]. This evidence concerns the gene IL6 and ovarian carcinoma.