They include, for example, Bacillus anthracis protective antigen (PA) against anthrax [12,13], fragment C of tetanus toxin (TetC) for tetanus [14], the outer surface protein A (OspA) of Borrelia burgdorferi against Lyme disease [15] and cytokines such as interferonα2b (IFNα2b) and IFN-γ [16,17] as well as a diabetes-associated autoantigen human proinsulin [18]. The gene discussed is INS; the disease is diabetes mellitus.