Although mesotheliomas have been known to secrete markers calretinin, mesothelin [6,10], CAM 5.2 [11], Alcian blue [12], Hale colloidal iron [12], vimentin [1,12], cytokeratin [1,12], calretinin [1], HBME-1 antigen [1], endothelial cell markers QBend-10 (CD 34), Factor VIII-related antigen (vWF) and UEA-1, panepithelial antibody (Lu-5) and membranous staining for BMA-120. This evidence concerns the gene VWF and mesothelioma.