MUC2 and esophageal adenocarcinoma: In SEG-1 esophageal adenocarcinoma cells treated with DCA (100 μM) for 18 hours, the basal levels of MUC2 and NF-κB p65 proteins were decreased by treatment with 4 mmol/L aspirin, there was also partial inhibition of the bile acid-dependent induction of MUC2 and NF-κB p65 (Fig. 5a).