IBSP and Alzheimer disease: In addition, as with AD differentiation, a four-day exposure to the treatments resulted in larger decreases in both ALP expression (3.8- and 9.2-fold for ouabain and K+, respectively, p<0.0001) and BSP expression by Day 7 (5.7-fold decrease for ouabain, p<0.0004, and undetectable levels for K+) (Fig. 9B, right).