We found that 10 genes already known to be associated with seizure or epilepsy have trans-QTLs with peak LOD scores near Szs1 and in Qrr1p. These include Scn1b, Cacna1g, Pnpo, and Dapk1 (Table S2) [75]–[84]. The gene discussed is SCN1B; the disease is epilepsy.