USP14 and cancer: High-level UBP6 expression was also detected in four other human cancers originating from mesenchymal neoplastic cells in a bone context (one Ewing's sarcoma, two osteoblastomas and one myofibroma), but not in 50 other non-ABC tumors, suggesting that UBP6 could have a broader oncogenic role in mesenchymal tumors [13].