EPHA2 and nuclear cataract: Since association was seen between SNPs in the EPHA2 region and cortical cataracts and suggestive results were obtained with nuclear cataracts, the analysis was extended to include any age-related cataracts with subsequent increased association in SNPs from the peak region to p<0.021 with the T-allele of rs7543472, although the G-allele of rs11260867 actually lost significance slightly (p=0.076).