CXCL12 and familial pancreatic carcinoma: Involvement of SDF-1/CXCR4 was reported during prostate cancer, ovarian cancer, colorectal cancer, hepatocellular carcinoma as well as pancreatic cancer (Hart et al, 2005; Jiang et al, 2006; Schimanski et al, 2006; Yoshitake et al, 2008).