Out of the 16 candidate genes, IPA identified a highly significant pathway (p-value ≈ 10-32) containing 12 of them FOXN1, PRDX3, SUCLA2, TFB2M, MED8, SNURF, DCTN2, PGK1, PRKCH, RYK, VAMP5 and PBLD, and this pathway most likely functioned in Cell Cycle, Cancer, Cell Death, and Hematological Disease (p-value range = 1.15 × 10-5, 1.03 × 10-1). The gene discussed is VAMP5; the disease is cancer.