SLC39A13 and Ehlers-Danlos syndrome: Slc39a13-KO mice also showed lipoatrophy; the subcutaneous layer of adipose tissue was significantly thinner in Slc39a13-KO than in wild-type mice (Figure 3A, lower left), a finding present also in the EDS patients (Case reports), suggesting that Slc39a13 may determine the fate of other mesenchymal-originated cells like adipocytes.