Although the specific issue of whether CLU is up- or down-regulated in CaP is still controversial [3], [13], [15], [59]–[61], confirmatory data supporting our hypothesis that CLU is not only down-regulated in CaP, but also in the most of cancers, can be easily retrieved from the Oncomine web site that collects data from more than 20,000 independent microarray experiments (http://www.oncomine.org). Here, CLU is linked to cancer.