ACTC1 and cardiomyopathy: To exclude mutations in other genes of high relevance in cardiomyopathies, the 18 initial mutation carriers were screened additionally for mutations in MYH7, TNNT2, TNNI3, ACTC and TPM1 encoding β-myosin heavy chain, cardiac troponin T, cardiac troponin I, cardiac α-actin and α-tropomyosin, respectively.