ACE and systemic lupus erythematosus: Furthermore, prednisolone treatment decreased serum creatinine levels to 0.67 ± 0.05 mg dL−1 in NZB/W F1 mice as did ACE treatment (serum creatinine = 0.69 ± 0.10 mg dL−1 in the 100 mg kg−1 ACE treatment group and 0.62 ± 0.07 mg dL−1 in the 400 mg kg−1 ACE treatment group) compared to SLE-disease group of NZB/W F1 mice (serum creatinine = 0.81 ± 0.14 mg dL−1).