In this regard, Stener-Victorin et al. [6,7] using electro-acupuncture (EA) for the treatment of polycystic ovarian syndrome (PCOS) have shown that repeated EA treatments in rats with steroid-induced PCOs, modulates nerve growth factor concentration in the ovaries and corticotropin releasing factor in the median eminence. Here, CRH is linked to polycystic ovary syndrome.