Conversely, a positive role of p38 has been shown in tumor suppression and delay of tumorigenesis [13], [14], in induction of apoptosis [15], [13], [16], in a specific tumor-suppressing defense mechanism of normal non transformed cells known as oncogene induction of senescence, [17], in dormancy [18], [19] and in the increased cell viability and enhanced growth of HPV-induced recurrent respiratory papillomatosis [20]. The gene discussed is MAPK14; the disease is neoplasm.