In one study, several oxidoreductase enzymes, including cytochrome oxidase, succinate dehydrogenase, monoamine oxidase, urate oxidase, D-amino acid oxidase, L-α-hydroxy acid oxidase, xanthine oxidase and catalase, were examined; the enzyme activities of all the oxidoreductase are steeply reduced in hepatoma, when compared to controls [15]. The gene discussed is DAO; the disease is hepatocellular carcinoma.