Galectin‐1 is a multifaceted promoter of glioma malignancy (8); galectin‐1 instigates increased glioma invasiveness through modifications to the actin cytoskeleton and increased Ras homolog gene family, member A small guanosine‐5′‐triphosphate (GTP)ase expression (6) and facilitates adhesion to the extracellular matrix (ECM) by cross‐linking glycoproteins (integrins) to ECM components (6). The gene discussed is ART4; the disease is glioma.