In univariate analyses, cases and controls differed with respect to age (p = 0.007), baseline CD4+ count (p = 0.03), co-infection with hepatitis B or C (p = 0.0008), smoking status (p = 0.0001), diabetes (p = 0.03), use of BP-lowering treatment (p = 0.02), and prior CVD (p = 0.04) (Table 1). This evidence concerns the gene CD4 and diabetes mellitus.