CRHBP and Familial prostate cancer: For example, a corticotropin-releasing hormone binding protein (CRHBP; Fig. 2B), and a mineralocorticoid receptor (NR3C2) were enriched in HVC, as were three genes with known androgen-related action, namely, an androgen-sensitive regulator of G-proteins (RGS4), which was enriched in HVC, and an androgen-induced prostate cancer RNA (TMEPAI) and an androgen regulated FERM domain containing protein (EPB41L2), which had lower expression in HVC.