After analysing the Cyr61 expression profile in the gene expression array-based database of human metastatic prostate tumours and primary prostate tumours (GSE6919), we found that the normal prostate tissues showed very low level of Cyr61 expression, whereas the tumour-adjacent tissues and the tumour tissues demonstrated a significantly higher expression level of Cyr61 (P<0.001, Figure 6F). This evidence concerns the gene CCN1 and prostate neoplasm.