Activated NF-κB plays a critical role in inflammation-driven tumour progression as it influences multiple processes such as cell-cycle control, apoptosis, stromal protease production and angiogenesis in addition to the release of inflammatory mediators including interleukin-8 (IL-8), which promotes tubular morphogenesis of endothelial cells (Shono et al, 1996). This evidence concerns the gene CXCL8 and neoplasm.