After 4 day of infection with a higher dose of rAd/Stat3 (moi = 1000), a cell viability assay (MTT) also revealed that WH and UMUC with higher content of p-Stat3 only maintained 34.8 ± 1.4% and 51.9 ± 8.5% cell viability of untreated controls (Figure 4C). This evidence concerns the gene STAT3 and infection.