Thus, TNBS colitis was characterized by an absence of significant changes in markers of T cells (Thy1, Tcrb, Tcrg, Zap70, Lck), B cells (Ptprc -B220-, Ms4a1 -Cd20-, Cd22, Cd79b) and NK cells (Baat, Ncam1 -Cd56-, B3gat1 -Cd57-). Here, CD22 is linked to colitis.