TNBS colitis influenced the expression of many transport-related transcripts, including genes that participate in ionic transport, e.g. Slc9a2, Slc9a3 (Nhe2-3), Scnn1a and Slc26a3 (Dra), which mediate NaCl absorption, and the Na+/K+ pump subunit Atp1a1 and Slc12a2 (Nkcc2), all of which were inhibited. The gene discussed is SLC12A1; the disease is colitis.