Real-time reverse transcription PCRwas used to study the mRNA levels of 18 genes (Table S4).We observed that both TLR8 transcripts, TLR8v1(p = 9.36×10−5),TLR8v2(p = 5.29×10−5)and MYD88 (NM_002468.3)(p = 4.09×10−5)were the most significantly upregulated in TB patients during active disease,relative to their convalescence. The gene discussed is MYD88; the disease is tuberculosis.