PTEN and neoplasm: In addition, those patients with high levels of cytoplasmic PTEN expression in their hormone-sensitive tumours were observed to have longer median overall survival (6.1 years (IQR 2.8–9.4)) compared to those with low PTEN expression (4.4 years (IQR 3.3–5.4)), although this did not reach significance (P=0.072; Figure 2C).