SGCA and autosomal recessive limb-girdle muscular dystrophy type 2D: Limb Girdle Muscular Dystrophy Type 2D (LGMD-2D) is an autosomal recessive disorder caused by mutations in the alpha sarcoglycan gene (sgca) and is the most prevalent of the sarcoglycanopathies; a class of dystrophies in which one of 6 transmembrane sarcoglycan proteins is deficient [1].