Table 8 shows that there was a higher occurrence of myringosclerosis in patients with normal serum PTH levels (22.7% compared to 10.8% in low serum PTH and 11.7% in elevated serum PTH levels); this finding, however, was not statistically significant (p = 0.192). At first sight, if there were a cause-effect relation between CRF and tympanosclerosis, the etiological and pathogenic mechanism of this condition would be similar to that found in vascular and visceral calcification, as Alfrey20 has reported. The gene discussed is PTH; the disease is tympanosclerosis.