Several ways to induce EMT in prostate cancer cells have been described, including overexpression of CAV1 and ID1 or MMP14 in LNCaP cells [13], [14], EGF treatment of DU145 cells [15], depletion of PDEF [16] or BMP7 treatment of PC3 cells [18]. This evidence concerns the gene MMP14 and Familial prostate cancer.