GH1 and Progressive cerebellar ataxia: Kuru most closely resembles iatrogenic CJD caused by peripheral administration of contaminated growth hormone (Brown et al. 1992, 2000, 2006; Billette de Villemeur et al. 1994; Will 2003) and a rare subtype of sCJD associated with long clinical duration, progressive ataxia and PRNP codon 129 heterozygosity (Parchi et al. 1996, 1999; Hill et al. 2003).