We found abundant expression of IL-33 in the nucleus of CD31+ or vWF+ endothelial cells from blood vessels in adenocarcinomas of the kidney (Figure 5A and B), stomach (Figure 5C and D), liver (Figure 5E and F), pancreas (Figure 5G and H), lung, breast or colon (data not shown). The gene discussed is IL33; the disease is adenocarcinoma.