DES and schwannoma: Histological and Immunohistochemical studies in our patients showed a mean maximum diameter of the schwannomas of 12,7 cm (7–20 cm), with areas of degeneration (cases 2, 4 and 5) and atypia (cases 1 and 3), while all were positive for vimentin and S-100 and negative for desmin, smooth muscle actin and HHF35.