A recent study demonstrated overexpression of NEK6 transcripts in hepatocellular carcinoma (Chen et al, 2006), although it was found to be frequently expressed among 125 serine/threonine kinase genes implicated in breast cancer, colorectal cancer, lung cancer, and laryngeal cancer by in situ hybridisation (Capra et al, 2006). Here, NEK6 is linked to breast cancer.