NOS3 and benign prostatic hyperplasia: During the genotyping of the -786T>C polymorphism of the NOS3 promoter [16], we have discovered and characterized three novel mutations [-764A>G, GenBank: NM_EF042808/-714G>T, GenBank: NM_EF042809/-649G>A, GenBank: NM_EF042810] in the PCa and BPH patients.