Differential expression of motility genes, including capping protein G (CAPG) and transforming growth factor beta-induced (TGFBI), was consistent with the reactive, migratory astrocyte phenotype characteristic of glaucoma [12], as were ECM remodeling genes, such as GPNMB [79,80] and TIMP1 [81,82]. The gene discussed is GPNMB; the disease is glaucoma.