The importance of astrocyte motility in the progression of glaucoma is a present focus of investigation [24]; the upregulation of CAPG in the experimental glaucoma samples as well as in immuno-enriched optic nerve head astrocytes from Caucasian American donors with glaucoma makes it a strong candidate as an astrocyte migratory gene in glaucoma. The gene discussed is CAPG; the disease is glaucoma.