RASSF1 and neoplasm: In the primary tumor specimens a positive correlation between RASSF1A expression and the pT stage (p = 0.001), histological grading (p = 0.029) and TNM group stage (p = 0.006) was detected, whereas no significant correlation was observed for lymph node metastasis (p = 0.377) and the presence of distant metastases (p = 0.41; table 2).