Blaney Davidson and colleagues [32] showed that BMP2 is associated with cartilage protection, chondrogenesis, and osteophyte formation in an animal model of osteoarthritis, and Badlani and colleagues [33] demonstrated that BMP7 protected the articular cartilage in a rabbit model of osteoarthritis, confirming the in vitro pro-anabolic and anti-catabolic properties of BMP7 as proposed by Chubinskaya and colleagues [34] and Fan and colleagues [35]. The gene discussed is BMP7; the disease is osteoarthritis.