AKT3 and hepatocellular carcinoma: Two previous studies failed to detect AKT3 mutations in clinical specimens of breast (n=154), colorectal (n=155), ovarian (n=50), gastric (n=180), hepatocellular carcinoma (n=68), non-small cell lung cancer (n=157), and adult acute leukaemias (n=129) (Carpten et al, 2007; Kim et al, 2008).