TACSTD2 and metastatic malignant neoplasm in the lymph nodes: Univariate analysis showed TROP2 overexpression to be significantly correlated with histologic grading (P=0.01) and the presence of lymph node metastases (P=0.04), but not with sex, age, T stage, presence of distant metastasis, or involvement of the resection margin (Table 2).