In contrast, those promoting Ca++ desensitization, such as the MLCPs (Ppm1a, Ppm1g, Pp2r2d, Ppp2r1a, Ppp1 catalytic subunit and Cdc42), were more highly expressed in the papillary adenocarcinoma tumors. The gene discussed is PPM1A; the disease is papillary adenocarcinoma.