SOCS1 and infection: A predominant Th1 immune response was observed during infection, as 6 of 11 investigated Th1 associated genes, including TNF, IFNG, and some IFNG-signaling responsive genes (SOCS1, STAT1, WARS and IRF1), were strongly up-regulated at 24 hpi and/or 48 hpi (Fig. 4B).