OLIG2 and experimental autoimmune encephalomyelitis: It will be of great interest to determine whether the Olig2+/GFAP+ cells generated in spinal cord injuries (Figure 3c), cerebral cortex stab injuries [21] and in rodent models of experimental autoimmune encephalomyelitis [20] are astrocytes generated from endogenous O-2A progenitor cells, and thus represent the long-sought in vivo counterpart of the type-2 astrocytes generated from these progenitor cells in vitro [40].