In all patients, high tumour grade was positively associated with negative hormonal receptor status (P<0.001), high Ki-67 labelling index (P<0.001) and high expression of CD34+ (P<0.01), CD68+ (P<0.05), CD4+ (P<0.05) and CD8+ (P<0.05) T lymphocytes. This evidence concerns the gene NR4A1 and neoplasm.