EGFR and neoplasm: The results showed that the protein expression of EGFR was significantly decreased in tumours from combination-treated mice as compared with all other treatments (relative density of EGFR in the EGCG+tamoxifen group was decreased by 85.3±3.33, 76.0±5.5 and 71.2±6.6% as compared with control, EGCG, and tamoxifen, respectively, P<0.001) (Figure 3A and B).