Recently, the AT-motif binding factor 1 (ATBF1)-A gene (GenBank: L32832), which has been assigned to chromosome 16q22.3-23.1 [9], was identified as a reasonable candidate for tumor suppressor activity in solid tumors, based on its functional inhibition of cell proliferation and high rate of mutations in prostate cancer [10]. This evidence concerns the gene ZFHX3 and Familial prostate cancer.